YOUR BRAIN, YOUR GENES: EXPLORING THE DNA BEHIND BRAIN INJURIES
- Dr. Elsie Cheng
- 4 days ago
- 2 min read

Medicine is changing fast, and one of the most exciting trends is personalized, targeted treatment. From cancer care to heart health, gene-based medicine is helping doctors understand not just what’s happening with a patient, but why, and how to tailor treatment to their unique biology. So when it comes to brain injuries, it makes sense to take the same approach.
Brain injuries can be really complicated and challenging to manage. Whether it’s a concussion, a traumatic brain injury, or even a seemingly minor bump on the head, symptoms like memory trouble, confusion, or mental fog can manifest. It’s natural to think the injury alone is causing everything. But science is showing us there might be more going on underneath the surface, right down in our genes.
Not everyone bounces back from a brain injury the same way. Some people recover in just a few weeks, while others struggle with symptoms for months or even longer. Why is that? Researchers are finding that our DNA holds some clues.
Thanks to breakthroughs in genetics, we now know that certain genes can influence not only how a brain injury happens but also how well someone recovers. For example, the APOE-e4 gene is linked to slower recovery and a higher chance of long-term challenges after a head injury. Other genes, like COMT, can affect how sensitive someone is to pain and how well they handle stress, while mutations in the MTHFR gene might cause fatigue or brain fog, even without an injury. These genes don’t cause brain injuries themselves, but they can definitely shape how a person feels and heals, and what kind of treatment might work best after a brain injury.
Looking at genetics and neurology isn’t about doubting someone’s symptoms. It’s about understanding the full story and giving everyone the care that fits them best. By combining genetic information with medical history and environmental factors, we can move past the “one-size-fits-all” model and get to a much smarter, more personal approach to recovery.
Sometimes people have hidden neurological or psychiatric conditions that haven’t been diagnosed yet, and these can affect how they respond to a brain injury. That’s why working with a neuropsychologists is so helpful as this is the specialty that can identify whether symptoms come from the injury or other underlying factors. Their expertise helps guide the right therapies and support plans tailored just for that person.
Our brains are influenced by a mix of things: inherited traits, the environment we live in, our lifestyles, and of course, injuries. When we take all of these into account, using genetic tests, brain assessments, and health histories, we get a much clearer picture of what’s really going on and how to help someone heal.
Brain science is moving forward every day, and with it, our approach to injury and recovery should advance too. Genetics doesn’t explain everything, but it gives us important data. By looking at the whole picture, the biology, the mind, and the environment, we can create better outcomes, offer more personalized care, and make decisions that truly help people get their lives back!
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